Pharmaceutical Science

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The Inhibitor Index: A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads


Daniel Purich
June 12, 2017

Metabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a proce...

Pharmaceutical Extrusion Technology, Second Edition

Isaac Ghebre-Sellassie, Charles E. Martin, Feng Zhang, James DiNunzio
March 16, 2018

The first edition of Pharmaceutical Extrusion Technology, published in 2003, was deemed the seminal book on pharmaceutical extrusion. Now it is expanded and improved, just like the usage of extrusion has expanded, improved and evolved into an accepted manufacturing technology to continuously mix...

Water-Insoluble Drug Formulation, Third Edition

Ron Liu
March 16, 2018

Properties and Formulation: From Theory to Real-World Application Scientists have attributed more than 40 percent of the failures in new drug development to poor biopharmaceutical properties, particularly water insolubility. Issues surrounding water insolubility can postpone or completely derail...

Lipase: An Industrial Enzyme Through Metagenomics

B.K. Konwar, Kalpana Sagar
March 15, 2018

Microbial lipases are industrially important and have gained their attention due to their stability, selectivity, and broad substrate specificity. Lipases are used as a medicine and also aid in indigestion, heartburn, allergy to gluten in wheat products (celiac disease), Crohn’s disease, and cystic...

Hydrogels: Design, Synthesis and Application in Drug Delivery and Regenerative Medicine

Thakur Raghu Raj Singh, Garry Laverty, Ryan Donnelly
February 28, 2018

Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue...

Handbook of Pharmaceutical Manufacturing Formulations: Volume Three, Liquid Products

Sarfaraz K. Niazi
February 26, 2018

While liquid drugs do not share the compression problems of solid dosage forms, the filling problems of powder dosage forms, or the consistency problems of semisolid dosage forms, they do have their own set of considerations in the formulation and manufacturing stages. Highlights from Liquid...

Natural Substances for Cancer Prevention

Jun-Ping Xu
February 21, 2018

Natural Substances for Cancer Prevention explores in detail how numerous investigations in chemical biology and molecular biology have established strong scientific evidence demonstrating how the properties of naturally occurring bioactive chemicals hamper all stages of cancers (from initiation to...

Nanoparticles in Life Sciences and Biomedicine

Ana Rute Neves, Salette Reis
February 15, 2018

The creation of new and more efficient therapies for improving human health greatly depends on drug delivery systems. Nanotechnology has emerged as a powerful strategy for the development of nanoparticles, such as nanoemulsions, liposomes, nanocrystals, and nanocomplexes, applied in the diagnosis,...

Pharmacy: What It Is and How It Works

William N. Kelly
February 14, 2018

Now fully updated for its fourth edition, Pharmacy: What It Is and How It Works continues to provide a comprehensive review of all aspects of pharmacy, from the various roles, pathways and settings of pharmacists to information about how pharmacy works within the broader health care system....

Chromatographic Techniques in the Forensic Analysis of Designer Drugs

Teresa Kowalska, Mieczyslaw Sajewicz, Joseph Sherma
February 06, 2018

There is a dramatic rise of novel drug use due to the increased popularity of so-called designer drugs. These synthetic drugs can be illegal in some countries, but legal in others and novel compounds unknown to drug chemistry emerge monthly. This thoughtfully constructed edited reference presents...

Measuring Elemental Impurities in Pharmaceuticals: A Practical Guide

Robert Thomas
February 02, 2018

Recent regulations on heavy metal testing have required the pharmaceutical industry to monitor a suite of elemental impurities in pharmaceutical raw materials, drug products and dietary supplements. These new directives s are described in the new United States Pharmacopeia (USP) Chapters <232>...

Asymmetric Synthesis of Drugs and Natural Products

Ahindra Nag
January 26, 2018

This book focuses on different techniques of asymmetric synthesis of important compounds, such as drugs and natural products. It gives insightful information on recent asymmetric synthesis by Inorganic, Organic and Enzymatic combinations. It also emphasizes chiral compounds and design of new...

Nanobiomaterials: Applications in Drug Delivery

Anil K. Sharma, Raj K. Keservani, Rajesh K. Kesharwani
January 08, 2018

This new volume focuses on the ever-growing and ever-sophisticated use of nanobiomaterials in drug delivery. There have been significant developments in the delivery of the active pharmaceutical ingredients to target sites, thereby sparing the normal functioning biological systems from damage, and...